More Data for Ustekinumab in Crohn’s Disease

Briefly noted: C Ma et al. Inflamm Bowel Dis 2017; 23: 833-9.  This retrospective study examined the response to ustekinumab in 104 patients with Crohn’s disease.  All patients had achieved a steroid-free ustekinumab induction.  92.3% had failed anti-TNFα therapy.

Key findings:

  • 71.8% maintained a response at 52 weeks
  • 64.4% maintained an endoscopic or radiographic response

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2 thoughts on “More Data for Ustekinumab in Crohn’s Disease

    • One reason for the impressive results was that all had undergone an ustekinumab induction and therefore had already responded. This study shows mainly that if one responds to ustekinumab, they are likely to maintain a response.

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